In Brief

The term "altered mental status" (AMS) encompasses a wide range of symptoms, from confusion and disorientation to significant changes in consciousness, behavior, or cognition. Within the ICD-10 classification system, the code 41.82 is designated for "Altered Mental Status, Unspecified," a diagnosis often used when a more precise underlying cause has yet to be determined. This blog post will explore the criteria and considerations for using this diagnosis, the importance of a thorough assessment to rule out medical and psychological conditions, and how clinicians can approach treatment planning while seeking a more definitive diagnosis. Understanding the nuances of AMS in the ICD-10 framework is crucial for providing comprehensive care and improving patient outcomes.
Prevalence of Altered Mental Status
Altered mental status affects many people. Certain groups, like older adults and those with neurological conditions, face a higher risk for altered mental status. Children can also experience it, though their symptoms and causes may differ from those in adults.

Diagnostic Criteria for Altered Mental Status
The DSM-5-TR does not provide specific diagnosis for altered mental status, although it is listed in the ICD-10. This diagnosis in the ICD-10 covers a wide range of presentations that may be covered by various diagnoses in the DSM-5-TR. The following conditions, which may appear as altered mental status, have DSM-5 diagnostic criteria:
- Delirium: This involves a disturbance in attention, awareness, and cognition that develops quickly and tends to fluctuate. The disturbance cannot be better explained by another preexisting, established, or evolving neurocognitive disorder and does not occur in the context of a severely reduced level of arousal, such as coma.
- Major Neurocognitive Disorder (Dementia): This is characterized by significant cognitive decline from a previous level of performance in one or more cognitive domains, like complex attention, executive function, learning and memory, language, perceptual-motor function, or social cognition. The cognitive deficits interfere with independence in everyday activities and are not exclusively in the context of a delirium or another mental disorder.
- Substance Intoxication and Withdrawal: This condition involves the development of a reversible substance-specific syndrome due to recent ingestion of or exposure to a substance. Symptoms may include significant problematic behavioral or psychological changes, such as impaired judgment, impaired social or occupational functioning, and altered mental status.
It's important to note that altered mental status is a symptom that can result from various medical, neurological, and psychiatric conditions, requiring a thorough evaluation, often by a medical doctor, to identify the underlying cause and appropriate diagnosis.

What Might Contribute to the Development of Altered Mental Status ICD-10
There can be various factors that can lead to an altered mental status, ranging from medical conditions to environmental and lifestyle influences. Some of the common factors may include things like neurological disorders (i.e., conditions like stroke, traumatic brain injury, and Alzheimer’s); substance use or withdrawal; environmental factors (i.e., exposure to toxins, extreme temperatures, or high altitude); and psychiatric conditions (i.e., severe depression; bipolar; schizophrenia).
It's important to note that due to the complexities in diagnosing altered mental status, medical doctors are the ideal provider to conduct a thorough evaluation to rule out or address any underlying medical conditions, as these often play a critical role in the presentation and management of altered mental status.

Altered Mental Status ICD-10 Management and Possible Interventions
When dealing with a patient experiencing altered mental status, the main aim is to identify and address the underlying cause while offering supportive care. The specific management strategies vary based on the individual's symptoms and the factors contributing to their altered mental status. Here are some general approaches to handling altered mental status:
- Ensure patient safety: Protect the patient from harm by creating a safe environment, preventing falls, and addressing any self-harm or suicidal thoughts.
- Refer for medical evaluation: This ensures that potential medical causes, such as infections, metabolic imbalances, or neurological conditions, are identified and addressed promptly, as they may require immediate intervention.
- Involve multidisciplinary team members: Work with specialists, such as neurologists, psychiatrists, or geriatricians, as needed to offer comprehensive care.
- Communicate with family and caregivers: Follow ethical and legal guidelines when keeping family members and caregivers informed about the patient's condition, treatment plan, and prognosis, and providing guidance on how to best support the patient during recovery.

Frequently Asked Questions (FAQ)
What is the ICD-10 code for altered mental status?
The ICD-10 code for altered mental status is R41.82. This code falls under the category of "Symptoms and signs involving cognition, perception, emotional state, and behavior" and the subcategory of "Other symptoms and signs involving cognitive functions and awareness."
Can altered mental status be diagnosed in children?
Yes, altered mental status can occur in children, although the causes and presentation may differ from those in adults. It's important to consider age-specific factors when evaluating and managing altered mental status in pediatric patients.
How is altered mental status different from delirium?
Altered mental status is a broad term that encompasses various changes in cognitive function, consciousness, or behavior, while delirium is a specific syndrome characterized by an acute onset of fluctuating confusion, inattention, and altered level of consciousness. Delirium is one of the many potential causes of altered mental status.
What are some common causes of altered mental status in older adults?
In older adults, common causes of altered mental status include infections (e.g., urinary tract infections, pneumonia), dehydration, electrolyte imbalances, medication side effects or interactions, and underlying neurological conditions such as dementia or stroke. Identifying and addressing these underlying factors is important for effective management.
How can mental healthcare professionals assess and manage patients with altered mental status?
When working with patients with altered mental status, mental healthcare professionals should focus on ensuring patient safety and coordinating care with involved health care providers, including medical doctors who are equipped to identify potential underlying causes. Mental healthcare providers should follow legal and ethical guidelines when communicating with family members and caregivers regarding the patient's condition and treatment plan.
Altered mental status, identified by the ICD-10 code R41.82, is a condition that requires quick recognition and action. It often appears in emergency departments and can affect people of all ages, although older adults and those with neurological conditions face a higher risk.
Managing altered mental status involves ensuring patient safety, identifying and addressing the root cause, and providing supportive care. A team approach, involving specialists such as neurologists, psychiatrists, or geriatricians, is necessary to offer comprehensive care.
